Solo and Small Practice EPCS Integration

If you’re a practitioner registered to an individual DEA number, getting started with EPCS isn’t as complex as it may sound. Just follow these four steps. You can also get started by contacting your EHR software vendor.

1. Update your EHR software

  • Find out if the EHR software version that your practice uses has already been certified and approved for EPCS
  • Click the "check" button to check your EHR status with Surescripts

2. Provide proof of ID

  • ID proofing can be done in-person or online, through companies that work with your EHR
  • For online ID proofing, you may need to answer a security question and email scanned copies of government-issued documents along with your photo and your medical license
  • Sometimes an electric bill or bank statement is also needed to confirm your address

3. Set up two-factor authentication

  • This double-level process ensures that only you can sign and send the controlled substance prescription to the pharmacy
  • There are various options: mobile phones, smart cards, fob tokens, USB thumb drives, and biometrics like fingerprint scanners
  • Once you’re set up, two-factor authentication requires hardly any extra effort

4. Implement secure access control

  • For this final step, you’ll need two separate people to set secure access controls for your EHR e-prescribing software
  • One person needs to be a DEA registrant who has been ID-proofed and has their two-factor authentication method in place—this could be you
  • The other is a person who can confirm your identity, such as an office manager or another member of your practice—but they do not need to be an employee of your practice

Once you’ve completed these four steps, you can get started using EPCS. You, your patients and pharmacists can enjoy the safety, security and convenience of EPCS.

For information specific to your software application, always consult with your EHR vendor.

Get the 4-step
reference sheet.


Check Your EHR Status with Surescripts

Find out if your software is EPCS-ready.

EPCS Helps Patients and Providers

patient safety

EPCS gives you access to your patient’s prescription history to help identify potential overuse. Abuse due to fraud can also be curtailed.

prescription process

There’s no need to change your workflow. EPCS lets you keep prescribing from within your EHR and can help improve workflow efficiency for prescribers and pharmacies.


EPCS provides accountability and security when prescribing controlled substances without sacrificing convenience. It’s a powerful tool for tackling the nation’s opioid crisis.